Do NOT use Requip if:

• you are allergic to any ingredient in Requip.

Some medical conditions may interact with Requip. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart problems, high or low blood pressure, liver disease, mental or mood problems, or a sleep disorder
• if you smoke, drink alcohol, or have a personal or family history of addiction (eg, gambling, alcohol).

Some medicines may interact with Requip. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
• Entacapone or levodopa because the risk of hallucinations may be increased
• Benzodiazepines (eg, diazepam), medicines for mental or mood problems (eg, antidepressants, antipsychotics), or medicines for sleep (eg, zolpidem) because the risk of severe drowsiness may be increased
• Estrogens (eg, estradiol), fluvoxamine, or quinolones (eg, ciprofloxacin) because they may increase the risk of Requip's side effects
• Butyrophenones (eg, haloperidol), metoclopramide, omeprazole, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Requip's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Requip may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

• Requip may cause dizziness, drowsiness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Requip with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
• Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Requip; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Requip may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Some people who use Requip may experience sudden onset of severe drowsiness or may even fall asleep during normal daily activities (eg, eating, talking, driving). This could occur without warning. If this happens, do not drive, operate machinery, or perform other possibly unsafe tasks while you use Requip. Tell your doctor right away.
• Some people have experienced new, unusual, or increased urges (eg, gambling, sexual urges) while using Requip. Tell your doctor right away if you notice such effects.
• Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
• Patients with Parkinson disease may have an increased risk of developing a certain type of skin cancer (melanoma). It is not known if Requip also increases the risk of melanoma. You may need to have skin exams while you are using Requip. Tell your doctor if you notice any unusual skin growths or a change in the appearance of a mole. Discuss any questions or concerns with your doctor.
• If you are taking Requip for RLS, contact your doctor if you experience new or worsening symptoms, especially in the early morning hours.
• Use Requip with caution in elderly patients with Parkinson disease; they may be more sensitive to its effects, especially hallucinations.
• Requip should not be used in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Requip while you are pregnant. It is not known if Requip is found in breast milk. Requip may decrease breast milk production. Do not breastfeed while taking Requip.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; dizziness; drowsiness; fatigue; headache; increased sweating; lightheadedness; loss of appetite; nausea; sore throat or flu-like symptoms; stomach pain or upset; tiredness; vomiting; weakness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; blood in the urine; blurred vision; chest pain; confusion; decreased coordination; fainting; falling asleep during the daytime or during normal activities (eg, conversations, eating); fast, slow, or irregular heartbeat; hallucinations; impotence; joint stiffness or pain; nightmares; numbness or tingling of the skin; severe or persistent headache or dizziness; shortness of breath; swelling of the arms or legs; uncontrolled muscle movements.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.